WHO investigates new BA.2.75 micron variant: does it have greater immune evasion?

The The World Health Organization (WHO) is investigating a new type of Omicron called Bachelor 2.75And the which was discovered in India early last month which It has already spread to 10 countries, in a spread that experts consider very rapid.

Swaminathan toxicityThe chief scientist of the World Health Organization in India said via social media that this variant “does not have an official name yet, but some scientists call it BA.2.75”. Make it clear to the world It is a “secondary variant for micron 2nd generation calls” and has “limited sequences that can be parsed, But he appears to have a few spikes in the spike protein and of course he has the key for the virus to enter the cell.”

For Swaminatahn, “It’s too early to tell if this variant has additional immune evasion properties. Or it could be more clinically dangerous” and still await what the WHO panel of scientists determines, “who analyzes data around the world.”

The expert further stated thatIt is a secondary variant that is very different from the previous one and has enough characteristics for us to watch with concern.” “We’ll have to wait and see, of course, that we’re monitoring that, and the WHO committee, TAG VE (Technical Advisory Group on the Evolution of Viruses) is constantly analyzing data from around the world,” the expert added. He explained: “At any time, if a virus appears that looks different enough from the previous one to be called a ‘Variable of Concern (VOC),’ the committee will do so.”

According to First International News, BA.2.75 contains 9 unusual spike protein mutations and has spread to countries around the world faster than other variants of this type. It was first found in a sequence captured in India in early June and Then it was discovered in Australia, Canada, Japan, Germany, New Zealand, the United Kingdom and the United States. Within weeks, the variant appeared in more than 80 sequences around the world. The number of mutations and their seemingly rapid spread over a wide geographical area keep scientists on alert.

Flechon tea, From the Central Laboratory of Virology at Sheba Medical Center in Tel Hashomer, Israel, he described the new alternative as “worrisome” and stressed that although it is too early to know if it will be the “next mainstream alternative,” it could point to the future. trend. Fleishon explained in a Twitter thread that in recent months there has been a trend of lineage-based variants of Omicron with mutations in the S1 section of the Spike protein andspecifically, in the part of the barbed protein that the virus uses to contact and enter cells, at a level not seen in second-generation variants.

So far, however, These second generation variants are only found in a few cases within a region. This is the first time a second generation variant of Omicron has been rolled out in multiple regions. Bloom’s lab at the Fred Hatch Research Institute tweeted that the variant was “worthy of observation” due to a “remarkable antigenic shift” compared to its mother, BA.2. The laboratory indicated two major mutations: G446S and R493Q.

Scholars agreed that more information is needed before it is known how important BA 2.75 is, and it is expected that in the coming weeks it will be known whether or not it can rival the BA.

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