August 15, 2022

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Science says: These are the vaccines against Covid-19 that can provide long-lasting protection

Science says: These are the vaccines against Covid-19 that can provide long-lasting protection

One study looked at the robustness of the protection offered by currently applied vaccines against COVID-19Compare it to the immunity naturally conferred by infection. According to this research, the current mRNA vaccines, Pfizer and modernThey are the ones that provide the longest duration of protection.

The unprecedented development of effective vaccines against SARS-CoV-2 represented a victory in global efforts to control the ongoing COVID-19 pandemic. Vaccines have been shown to provide short-term protection against major adverse health outcomes of hospitalization and death.” Proceedings of the National Academy of Sciences (PNAS)

In this framework, they state that protection against new infections decreases over time, and that vaccines Provides longer-lasting immunity than the antibodies that infection naturally producesHighlighting the need for booster vaccination to reduce infection and inflammation.

Research supports the need to give boosters and keep vaccinations up to date.

Details of the study on the duration of immunity against Covid-19

In this regard, the study found that the current mRNA vaccine, Pfizer and Moderna, Provides longer protection than Johnson & Johnson and Oxford-AstraZenecaand greater than the natural infection.

It gave a natural infection An average of 21.5 months of protection against progressive infection, while the mRNA vaccines produced by Pfizer-BioNTech and Moderna induced higher antibody levels than normal infection, resulting in an average time to increased infection 29.6 months.

The authors found that the viral vector vaccines produced by Oxford-AstraZeneca and Johnson & Johnson/Janssen elicited levels of antibodies similar to those produced by natural infections, with a mean time to onset of infection. 22.4 months and 20.5 months, respectively.

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Jeffrey Townsend “MRNA vaccines produce the highest levels of antibody response and in our analysis confer protection that lasts longer than vaccines or other exposures,” explained the Yale University School of Public Health professor and lead author of the study.

“However, it is important to remember that Natural immunity and vaccination are not mutually exclusive. Many people will have partial immunity from multiple sources, so understanding relative robustness is key to deciding when to boost your immune system.”

In this sense, the scientists stated that reliable protection against reinfection “requires an updated boost with vaccines designed to address changes in the virus that occur as part of its natural evolution over time.”

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Alex Dornberg, At this point it’s important to keep in mind that the virus “will develop ways to evade our natural immune response and any immune response derived from the vaccine,” said an assistant professor at the University of North Carolina at Charlotte, who led the study with Townsend.

That’s why, together with Townsend, they considered the constant update of our vaccines and booster shots “It is essential to our fight against SARS-CoV-2.”

AG / CCM

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