Can infection increase the risk of Alzheimer’s disease?

Every 3 seconds, someone in the world evolves mental illness. This is the seventh major reason for the death between every diseases And one of the main reasons for inability s Accreditation between the the elderly all over the world.

The Alzheimer’s disease It is not a normal part of aging. that it Irreversible degeneration From brain which causes changes in memoryThe knowledge, The Personal And other jobs that eventually lead to death from brain failure complete. Currently, more than 55 million People live with dementia all over the world and there are almost 10 million dollars of new cases every year.

specialists Swedish Karolinska Institute Publish an investigation in the specialized journal PlusAnd the Which indicates that people who are being treated in hospital infections they can get higher risks to develop Alzheimer’s disease early mode After years.

Experimental animal studies have suggested that Infection plays a role in the development of some neurodegenerative diseases, However, supporting evidence in humans is limited. jianghui sun, The first author of the researcher and specialist inKarolinska InstituteHe and his colleagues analyzed health records everywhere 290,000 people in Sweden With Alzheimer’s disease and 1.4 million people Suitable for age and gender Not diagnosed with disease.

Among those previously diagnosed with Alzheimer’s disease 60 yearsThe 17.4 percent were treated in hospital for an infection at least five years ago, compared to 9.8 percent of age-matched people without a diagnosis of Alzheimer’s disease.

The Bacterial infections and those of the urinary system and reproductive organs were more associated with an increased risk of Alzheimer’s disease, But it was also noted viral infections and those The central nervous system s Digestive.

The researchers took into account Differences in education of the people and of them family background From Neurological diseases and other terms, including Cardiovascular disease and diabetes. Several previous studies have hinted at possible links between Alzheimer’s disease and specific pathogens, such as Herpes viruses. The findings build on this by adding evidence of a general link between the infection and the condition.

Despite the abundance of preclinical data, there are not many well-conducted observational studies in this area. Therefore, the results of the current study should be considered as an important addition.” The results are largely consistent with the concept, Supported by nearly 500 articles Using a variety of methods, including Microbes play an important role in Alzheimer’s disease.

These findings suggest that infectious events may be a trigger or amplifier of a pre-existing disease process, leading to clinical onset at a relatively young age. “because of The observational nature of the study, These results They have not formally established a causal link.Sun concluded.

There are many different forms of dementia. illness Alzheimer’s disease is the most common form and can contribute to 60 to 70% of cases. Dementia can also develop after an injury brain attack Or in the context of some types of infection such as human immunodeficiency virus, The Harmful use of alcohol, repeated physical injury to the brain (commonly known as chronic traumatic encephalopathy) or nutritional deficiency Worldwide, about 55 million people suffer from dementia, and More than 60% live in low and middle income countries. As the proportion of older people in the population is increasing in almost all countries, this number is expected to rise to 78 million in 2030 and 139 million in 2050.

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